The Think-in is a two-day event focusing on the theme “Design of safe and secure Cyber Physical Systems (CPS).” The first day will include a sequence of four brainstorming sessions. Each session will be devoted to a specific sub-topic under the general theme led by a panel of experts. These experts will present key issues within the sub-theme and the state of the art techniques and tools to address these issues. Presentation by the panelists will be followed by a discussion involving key discussants as well as all event attendees focusing on the strengths and limitations of the existing tools and techniques. This discussion is expected to lead to proposals for further research and potential international collaborations. The entire discussion during the first day will be summarised and compiled into a report.